Kiel Life Science

Prof. Dr. rer. nat. Susanne Sebens

Institute of Experimental Cancer Research, University Medical Center Schleswig-Holstein, Campus Kiel

Arnold-Heller-Straße 3, Haus 17, 24105 Kiel
Phone: +49 431 500 30501
Telefax: +49 431 500 30502

Faculty of Medicine

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Research interests

Since inflammatory processes essentially contribute to the initiation and progression of tumors, inflammation has been defined as a hallmark of cancer. This also applies to gastrointestinal tumors such as pancreatic ductal adenocarcinoma (PDAC) which is in the focus of our research. The research group Inflammatory Carcinogenesis aims at gaining a better understanding of the molecular and cellular interactions by which inflammatory cells (myofibroblasts, macrophages and T-cells) promote tumor initiation and outgrowth of metastases. Thereby, novel target structures will be identified to improve diagnosis and therapy of highly malignant tumors such as PDAC. Our research is based on sophisticated coculture model systems comprising epithelial cells and different inflammatory cells with subsequent expression and functional analysis. Moreover, all findings are validated in animal based studies and/or patient derived material. Our research is conducted in close interdisciplinary collaboration with different institutions of the University Hospital Schleswig-Holstein and the Christian-Albrechts-University. The research group is involved in the master programs Biology, Biochemistry and Medical Life Sciences.

Current Research



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